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2004-2010 | 2011-2015 | 2016-


Das, S.; Stark, L.; Musgrave, I.; Pukala, T.L.; Smid, S.D.
Bioactive polyphenol interactions with β amyloid: a comparison of binding modelling, effects on fibril and aggregate formation and neuroprotective capacity
Food & Function, 2016; 7:1138-1146

Calabrese, A.N.; Liu, Y.; Wang, T.; Musgrave, I.F.; Pukala, T.L.; Tabor, R.F.; Martin, L.L.; Carver, J.A.; Bowie, J.H.
The amyloid fibril-forming properties of the amphibian antimicrobial peptide uperin 3.5
ChemBioChem, 2016; 17(3):239-246


Liu, Y.; Graetz, M.; Ho, L.; Pukala, T.L.
Ion mobility–mass spectrometry-based screening for inhibition of α-synuclein aggregation
European Journal of Mass Spectrometry, 2015; 21:255–264

Calabrese, A.N.; Bowie, J.H.; Pukala, T.L.
Structural analysis of calmodulin binding by nNOS inhibitory amphibian peptides
Biochemistry, 2015; 54(2):567-76


Liu, Y.; Carver, J.A.; Ho, L.H.; Elias, A.K.; Musgrave, I.F.; Pukala, T.L.
Hemin as a generic and potent protein misfolding inhibitor
Biochemical and Biophysical Research Communications, 2014; 454(2):295-300

Liu, Y.; Carver, J.A.; Calabrese, A.N.; Pukala, T.L.
Gallic acid interacts with alpha-synuclein to prevent the structural collapse necessary for its aggregation
Biochimica et Biophysica Acta, 2014; 1844(9):1481-5


Calabrese, A.; Pukala, T.
Chemical cross-linking and mass spectrometry for the structural analysis of protein assemblies
Australian Journal of Chemistry, 2013; 66(7):749-59

Pukala, T.
Mass spectrometry: mapping large stable protein complexes
Encyclopedia of Biophysics (G Roberts, ed) pp. 1422-9, Springer, Germany, 2013

Liu, Y.; Pukala, T.L.; Musgrave, I.F.; Williams, D.M.; Dehle, F.C.; Carver, J.A.
Gallic acid is the major component of grape seed extract that inhibits amyloid fibril formation
Bioorganic & Medicinal Chemistry Letters, 2013; 23(23):6336-40

Scott, D.E.; Ehebauer, M.T.; Pukala, T.; Marsh, M.; Blundell, T.L.; Venkitaraman, A.R.; Abell, C.; Hyvonen, M.
Using a fragment-based approach to target protein-protein interactions
ChemBioChem, 2013; 14(3):332-42

Cottam, J.; Scanlon, D.; Karas, J.; Calabrese, A.; Pukala, T.; Forbes, B.; Wallace, J.; Abell, A.
Chemical synthesis of a fluorescent IGF-II analogue
International Journal of Peptide Research and Therapeutics, 2013; 19(1):61-69

Calabrese, A.N.; Wang, T.; Bowie, J.H.; Pukala, T.L.
Negative ion fragmentations of disulfide-containing cross-linking reagents are competitive with aspartic acid side-chain-induced cleavages
Rapid Communications in Mass Spectrometry, 2013; 27(1):238-48

Williams, D.M.; Pukala, T.L.
Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry
Mass Spectrometry Reviews, 2013; 369-87(32):169-87


Calabrese, A.N.; Speechley, L.A.; Pukala, T.L.
Characterisation of calmodulin structural transitions by ion mobility mass spectrometry
Australian Journal of Chemistry, 2012; 65(5):504-11

Leung, M.H.M.; Mohan, P.; Pukala, T.L.; Scanlon, D.B.; Lincoln, S.F.; Kee, T.W.
Reduction of copper(ii) to copper(i) in the copper-curcumin complex induces decomposition of curcumin
Australian Journal of Chemistry, 2012; 65(5):490-5

McColl, G.; Roberts, B.R.; Pukala, T.L.; Kenche, V.B.; Roberts, C.M.; Link, C.D.; Ryan, T.M.; Masters, C.L.; Barnham, K.J.; Bush, A.I.; Cherny, R.A.
Utility of an improved model of amyloid-beta (Abeta 1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease
Molecular Neurodegeneration, 2012; 7:57

Calabrese, A.N.; Good, N.J.; Wang, T.; He, J.; Bowie, J.H.; Pukala, T.L.
A negative ion mass spectrometry approach to identify cross-linked peptides utilizing characteristic disulfide fragmentations
Journal of the American Society for Mass Spectrometry, 2012; 23(8):1364-75


Liu, Y.; Ho, L.H.; Carver, J.A.; Pukala, T.L.
Ion mobility mass spectrometry studies of the inhibition of alpha synuclein amyloid fibril formation by (–)-epigallocatechin-3-gallate
Australian Journal of Chemistry, 2011; 64(1):36-40

Pukala, T.L.
Mass spectrometry for structural biology: determining the composition and architecture of protein complexes
Australian Journal of Chemistry, 2011; 64(6):681-91

Jackway, R.J.; Pukala, T.L.; Donnellan, S.C.; Sherman, P.J.; Tyler, M.J.; Bowie, J.H.
Skin peptide and cDNA profiling of Australian anurans: genus and species identification and evolutionary trends
Peptides, 2011; 32(1):161-72

Sanchez, L.; Madurga, S.; Pukala, T.; Vilaseca, M.; Lopez-Iglesias, C.; Robinson, C.V.; Giralt, E.; Carulla, N.
Aβ40 and Aβ42 amyloid fibrils exhibit distinct molecular recycling properties
Journal of the American Chemical Society, 2011; 133(17):6505-8

Wang, T.; Andreazza, H.J.; Pukala, T.L.; Sherman, P.J.; Calabrese, A.N.; Bowie, J.H.
Histidine-containing host-defence skin peptides of anurans bind Cu2+. An electrospray ionisation mass spectrometry and computational modelling study
Rapid Communications in Mass Spectrometry, 2011; 25(9):1209-21


Pukala, T.L.; Ruotolo, B.T.; Zhou, M.; Politis, A.; Stefanescu, R.; Leary, J.A.; Robinson, C.V.
Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements
Structure, 2009; 17(9):1235-43

Doyle, J.R.; Bowie, J.H.; Jackway, R.J.; Llewellyn, L.E.; Pukala, T.L.; Apponyi, M.A.; Booker, G.W.
Anuran host-defense peptides that complex with Ca2+ calmodulin and inhibit the synthesis of the cell signaling agent nitric oxide by neuronal nitric oxide synthase
Bioactive Peptides (J Howl and S Jones, eds) pp. 315-32, Taylor and Frances Publishing Group, UK, 2009


Gehman, J.D.; Luc, F.; Hall, K.; Lee, T.H.; Boland, M.P.; Pukala, T.L.; Bowie, J.H.; Aguilar, M.I.; Separovic, F.
Effect of antimicrobial peptides from Australian tree frogs on anionic phospholipid membranes
Biochemistry, 2008; 47(33):8557-655

Pukala, T.L.; Urathamakul, T.; Watt, S.J.; Beck, J.L.; Jackway, R.J.; Bowie, J.H.
Binding studies of nNOS-active amphibian peptides and Ca2+ calmodulin, using negative ion electrospray ionisation mass spectrometry
Rapid Communications in Mass Spectrometry, 2008; 22(22):3501-9

Jackway, R.J.; Pukala, T.L.; Maselli, V.M.; Musgrave, I.F.; Bowie, J.H.; Liu, Y.; Surinya-Johnson, K.H.; Donnellan, S.C.; Doyle, J.R.; Llewellyn, L.E.; Tyler, M.J.
Disulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: structure, activity and evolutionary trends
Regulatory Peptides, 2008; 151(1-3):80-7


Pukala, T.L.; Doyle, J.R.; Llewellyn, L.E.; Kuhn-Nentwig, L.; Apponyi, M.A.; Separovic, F.; Bowie, J.H.
Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase
The FEBS Journal, 2007; 274(7):1778-84

Pukala, T.L.; Boland, M.P.; Gehman, J.D.; Kuhn-Nentwig, L.; Separovic, F.; Bowie, J.H.
Solution structure and interaction of cupiennin 1a, a spider venom peptide, with phospholipid bilayers
Biochemistry, 2007; 46(11):3576-85


Pukala, T.L.; Bertozzi, T.; Donnellan, S.C.; Bowie, J.H.; Surinya-Johnson, K.H.; Liu, Y.; Jackway, R.J.; Doyle, J.R.; Llewellyn, L.E.; Tyler, M.J.
Host-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea
The FEBS Journal, 2006; 273(15):3511-9

Pukala, T.L.; Bowie, J.H.; Maselli, V.M.; Musgrave, I.F.; Tyler, M.J.
Host-defence peptides from the glandular secretions of amphibians: structure and activity
Natural Product Reports, 2006; 23(3):368-93


Brinkworth, C.S.; Pukala, T.L.; Bowie, J.H.; Tyler, M.J.
Host defence peptides from the skin glands of Australian amphibians. Caerulein neuropeptides and antimicrobial, anticancer, and nNOS inhibiting citropins from the Glandular Frog Litoria subglandulosa
Australian Journal of Chemistry, 2004; 57(7):693-701

Pukala, T.L.; Brinkworth, C.S.; Carver, J.A.; Bowie, J.H.
Investigating the importance of the flexible hinge in caerin 1.1: solution structures and activity of two synthetically modified caerin peptides
Biochemistry, 2004; 43(4):937-44

Apponyi, M.A.; Pukala, T.L.; Brinkworth, C.S.; Maselli, V.M.; Bowie, J.H.; Tyler, M.J.; Booker, G.W.; Wallace, J.C.; Carver, J.A.; Separovic, F.; Doyle, J.; Llewellyn, L.E.
Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Peptides, 2004; 25(6):1035-54

Pukala Research Group
Please direct any enquiries to:

Dr Tara Pukala
School of Physical Sciences
The University of Adelaide
SA 5005


T: +61 8 8313 5497